Adjunct Professor, Department of Geological Sciences, University of Saskatchewan
Assistant Director and Lab Manager, Illinois EPR Research Center
Telphone: 217-333-3969
Fax: 217-333-6686
E-mail: _mjnilges_ at_illinois.edu_
Recent Publications:
M. Mao, M. J. Nilges & Y. Pan, “Radiation-induced defects in apophyllites. II. An O- centre and O−−O− pairs in hydroxylapophyllite,” European Journal of Mineralogy, 22:ppp(2010). [Abstract]
E. Rodríguez, M. Nilges, R. Weissleder, and J. W Chen, “Activatable magnetic resonance imaging agents for myeloperoxidase sensing: mechanism of activation, stability and toxicity,” J. Am. Chem. Soc., 132:168–177(2010). [Abstract]
N. M. Marshall, D. K. Garner, T. D. Wilson, Y. Gao, H. Robinson, M. J. Nilges and Y. Lu, “Rationally Tuning the Reduction Potential of a Single Cupredoxin Beyond the Natural Range,” Nature, 462:113-6(2009). [Abstract]
G. S. Siluvai, M. M. Nakano, M. J Nilges, and N. J Blackburn, “H135A Controls The Redox Activity of the Sco Copper Center. Kinetic and Spectroscopic Studies of the His135Ala Variant of Bacillus Subtilis Sco,” Biochemistry, 48:12133–12144(2009). [Abstract]
Y. Pan, M. J. Nilges, and R. Mashkovtsev, “Radiation-induced defects in quartz: Multifrequency EPR study and DFT modeling of new peroxy radicals,” Mineralogical Magazine, 73:521–537(2009). [Abstract]
Nilges, M.J., Pan, Y. & Mashkovtsev, R.I. “Radiation-induced defects in quartz. Part III. W-band EPR, ENDOR and ESEEM study of a peroxy radical., Phys. Chem. Minerals., 36:61–73 (2009). [Abstract]
J. Backiel, O. Juárez, D. V. Zagorevski, Z. Wang, M. J. Nilges, and B. Barquera, “RnfG and RnfD bind FMN covalently in the Rnf complex from Vibrio cholerae,” Biochemistry, 47:11273–11284 (2008). [Abstract]
O. Juárez, M. J. Nilges, P. Gillespie, J. Cotton, and B. Barquera, “Riboflavin Is an Active Redox Cofactor in the Na+-pumping NADH:Quinone Oxidoreductase (Na+-NQR) from Vibrio cholerae,” J. Biol. Chem.,283:33162-33167 (2008). [Abstract]A. K. Justice, L. De Gioia, M. J. Nilges, T. B. Rauchfuss, S. R. Wilson, and G. Zampella, “Redox and Structural Properties of Mixed-Valence Models for the Active Site of the [FeFe]-Hydrogenase: Progress and Challenges,” Inorg. Chem. 47:7405–7414 (2008). [Abstract]
Y. Pan, M. J. Nilges, and R. Mashkovtsev, Radiation-induced defects in quartz. Part II. “Single-crystal W-band EPR study of hole centers in a citrine quartz,” Phys. Chem. Minerals., 35:387–397 (2008).
Botis, S., Pan, Y., Nokhrin, S. & Nilges, M.J., Natural radiation-induced damage in quartz. III. A single-crystal EPR study of drusy quartz from the Athabasca basin, Saskatchewan. Canadian Mineralogist, Vol. 46: 122-135(2008). [Abstract]
M. G. Savelieff, T. D. Wilson, Y. Elias, M. J. Nilges, D. K. Garner, and Y. Lu, “Experimental evidence for a link among cupredoxins: Red, blue, and purple copper transformations in nitrous oxide reductase,” PNAS, 105: 7919-7924(2008). [Abstract]
A. K. Justice, M. J. Nilges, T. B. Rauchfuss, S. R. Wilson, L. De Gioia and G. Zampella, “Diiron Dithiolato Carbonyls Related to the HoxCO State of [FeFe]-Hydrogenase,” J. Am. Chem. Soc.; 130, 5293–5301, (2008). [Abstract]
Botis, S., Pan, Y., Nokhrin, S. and Nilges, M.J., Natural radiation-induced damage in quartz. III. A single-crystal EPR study of drusy quartz from the Athabasca basin, Saskatchewan. Canadian Mineralogist, Vol. 46: 122-135(2008). [Abstract]
M. J. Nilges, Y. Pan, and R. Mashkovtsev,
Radiation-damage-induced defects in quartz. I. Single-crystal W-band
EPR study of hole centers in an electron-irradiated quartz, Phys. Chem.
Minerals.,35:103–115 (2008). [Abstract]
R. A. Pugh, M. Honda, H. Leesley, A. Thomas, Y. Lin, M.
J.Nilges, I. K.O. Cann, and M. Spies, The iron-containing domain is
essential in RAD3 helicases for coupling
of ATP hydrolysis to DNA translocation and for targeting the helicase
to the ssDNA-dsDNA junction. J Biol Chem., 283, 1732-1743 (2008). [Abstract]
B. Barquera, L. Ramirez-Silva, J. E. Morgan, and
M. J. Nilges, ‘A new flavin radical signal in the Na+-pumping NADH:
Quinone
oxidoreductase from Vibrio cholerae: An EPR/ENDOR investigation of the
role of
the covalently bound flavins in subunits B and C,” J. Biol. Chem., 281,
36482-36491(2006). [Abstract]
M. J. Nilges, K. Matteson, R.L.Belford, “SIMPOW6: A software package for the simulation of ESR powder-type spectra” in ESR Spectroscopy in Membrane Biophysics, Biological Magnetic Resonance, Vol. 27, Hemminga, Marcus A., and Berliner, Lawrence Eds. Springer, New York, ISBN: 0-387-25066-2 (2006).
S. M. Nokhrin, Y. Pan, and M. J. Nilges, “Electron paramagnetic resonance spectroscopic study of carbonate-bearing fluorapatite: New defect centers and constraints on the incorporation of carbonate ions in apatites,” American Mineralogist, 91, 1425-1431(2006). [Abstract]Blanca Barquera, Mark J. Nilges, Joel E. Morgan, Leticia Ramirez-Silva, Weidong Zhou, and Robert B. Gennis, " Mutagenesis Study of the 2Fe-2S Center and the FAD Binding Site of the Na+-Translocating NADH:Ubiquinone Oxidoreductase from Vibrio cholerae," Biochemistry, 43(38); 12322-12330(2004) [Abstract]
Martina Ralle, Steven M. Berry, Mark J. Nilges, Matt D. Gieselman, Wilfred A. van der Donk, Yi Lu, and Ninian J. Blackburn, "The Selenocysteine-Substituted Blue Copper Center: Spectroscopic Investigations of Cys112SeCys Pseudomonas aeruginosa Azurin," J. Am. Chem. Soc.; 126(23), 7244-7256(2004); [Abstract]
Hurth, K. M.; Nilges, M. J.; Carlson, K. E.; Tamrazi, A.; Belford, R. L.; Katzenellenbogen, J. A.; "Ligand-Induced Changes in Estrogen Receptor Conformation As Measured by Site-Directed Spin Labeling," Biochemistry ; 43(7), 1891-1907(2004); [Abstract]
P. Rahimi-Moghaddam, Y. Upadrashta, M.J. Nilges, and J.A. Weil, “EPR of Manganese-Containing Plasticine -Spectral Simulation and Use as an Internal Standard for Comparison of the Single Intensities of Various Free-Radical EPR Spectra,” Appl. Magn. Res., 24, 13-125(2003); [Abstract]
Barquera, B., Morgan, J. E., Lukoyanov, D., Scholes, C. P., Gennis, R. B., and Nilges, M. J., "X- and W-band EPR and Q-band ENDOR studies of the flavin radical in the Na+-translocating NADH:quinone oxidoreductase from Vibrio Cholerae," J. Am. Chem. Soc., 125, 265-275(2003); [Abstract]
Pan, Y., Fleet, M.E., Chen, N., Weil, J. A., and Nilges, M. J., "Site preference of Gd in synthetic flourapatite by single-crystal W-band EPR and X-ray structure refinement: A comparative study," Canadian Mineralogist, 40,1103-1112(2002); [Abstract]
Pan, Y., Chen, N., Weil, J. A., and Nilges, M. J., Structural characterization of sub-ppm-level trace elements: Single-crystal W-band EPR study of Gd and Mn in fluorapatite, American Mineralogist, 87, 1333-1341(2002); [Abstract]
Steven M. Berry, Matt D. Gieselman, Mark J. Nilges, Wilfred A. van der Donk, and Yi Lu ; An Engineered Azurin Variant Containing a Selenocysteine Copper Ligand, Journal of the American Chemical Society; 124(10); 2084-2085(2002); [Abstract]
Blanca Barquera, Petra Hellwig, Weidong Zhou, Joel E. Morgan, Claudia C. Häse, Khoosheh K. Gosink, Mark Nilges, Peter J. Bruesehoff, Annette Roth, C. Roy D. Lancaster, and Robert B. Gennis ; Purification and Characterization of the Recombinant Na+-Translocating NADH:Quinone Oxidoreductase from Vibrio cholerae, Biochemistry; 41(11); 3781-37899(2002); [Abstract]
Electron paramagnetic resonance spectroscopic study of synthetic fluorapatite: Part II. Gd3+ at the Ca1 site, with a neighboring Ca2 vacancy, Ning Chen, Yuanming Pan, John A. Weil, and Mark J. Nilges, American Mineralogist, 87, 47-55(2002); [Abstract]